题目：C(sp³)–S Bond Formation via the Synergy of Oxidative With Reductive Photocatalysts Through Photoredox and Dual Hydrogen Atom Transfer Processes

作者：Chao Zhou,^a(周超) Qianli Liang,^aXinyi Zhu,^aXue Zhang,^aLimei Liu,^aYicheng Zhang,*^,aJie Liu,^aXiaoyu Xie,*^,aand Lei Wang*^,a,b,c

单位：^aCollege of Chemistry and Materials Science, Key Laboratory of Green and Precise Synthetic Chemistry, Ministry of Education, Huaibei Normal University, Huaibei, Anhui 235000, P. R. China.

^bAdvanced Research Institute and School of Pharmaceutical Sciences, Taizhou University, Taizhou, Zhejiang 318000, P. R. China.

^cCollege of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou, Zhejiang, 311121, P. R. China.

摘要：A primary objective of organic synthesis is to establish a catalytic methodology that is mild, straightforward, and economically efficient. Thioesters are widely employed in the realms of physiology, pharmacology, and agriculture. It is imperative to continuously expand the range of sulfur-containing precursors to keep pace with the cutting-edge advancements in the field of organic sulfurchemistry. Our research has uncovered that polysulfide anions(K₂S_x), which serve as reducing catalysts, can also effectively act as sulfur reagents,providingthe formation of C(sp³)–S bonds throughaphotoredox catalysis withan oxidativephotocatalyst tetrabutylammonium decatungstate(TBADT) anddualhydrogen atom transfer (DHAT) process.In a pioneering study, we present a combinatorial strategyofan oxidativephotocatalyst TBADTwitha reductivephotocatalyst K₂S_x,enabled a photo-induced three-componentcoupling reactionofsimple aldehydeswith alkanes containing C(sp³)–Handpolysulfide anions. Anumbers ofthioester derivatives weresuccessfullyobtained in good yields, whileaby-product H₂S was captured and identifiedbygas chromatography analysis.Concurrently, density functional theory (DFT) calculations providedthetheoreticalsupport ofreaction mechanism.

影响因子：14.1

分区情况：一区

链接：https://doi.org/10.1002/advs.202415936

年、卷、页：2025, e15936.

（文、图：周超 / 审核：韩满意 / 审校：曹静 / 终审：杨振兴）